PUBLIC PROJECTS
- GOVERNMENT AGENCY: Ministry of Interior of Italy
The Asylum, Migration and Integration Fund (AMIF) 2014-2020
Specific objective 1. Asylum - National objective 1 - Reception / Asylum - lett. c - Strengthening the 1st and 2nd reception system - Health protection, has made it possible to improve the quality of the programs and services of the National Health Service offered to asylum seekers and holders of international protection present in the Apulian territory
TITLE
Model for Reception and Health Integration (MISA)
GROUP:
IFO – San Gallicano IRCCS
PI Prof. Aldo Morrone
ABSTRACT
- sharing within the regional health system an integrated model for the prevention, diagnosis, and treatment of dermatological, (in particular, post-traumatic stress related ones), sexually transmitted, and oncological diseases.
- to improve the knowledge of procedures for taking charge of prevention, diagnosis, and treatment of the abovementioned pathologies; to improve the skills of centre’s operators and of health professionals; to improve the level of health protection for the beneficiaries.
- Research-action; trials for an integrated model of prevention, diagnosis, and treatment of the abovementioned pathologies; training of health professionals; training of centre operators; trial of “Health Desks”; communication and networking.
- methodology in line with the objectives: starting from an initial survey of the critical issues and further trialling a model able to address them (knowing before acting).
- To manage critical issues for health care; 30 trained centre operators; 80 trained regional health system’s health workers; 200 assisted vulnerable having applied for or having been granted international protection; activation of 2 “Health Desks”; contribute to the removal of organisational and cultural barriers to use and access of regional health services and to the protection of beneficiaries’ health status.
- GOVERNMENT AGENCY: Ministry of Interior of Italy
The Asylum, Migration and Integration Fund (AMIF) 2014-2020
Specific Objective 2. Integration / Legal Migration - National Objective NO 3 - lett j) Governance of services
TITLE
Mi.Fa.Bene. – Minors, Family, Welfare
GROUP
Capofila Roma Capitale
"La Sapienza" University of Rome
IFO – San Gallicano IRCCS
P.I. Prof. Aldo Morrone
ABSTRACT
To share a new integrated standard procedure for promoting health in foreign/migrant minors. In particular, the protocol should focus on prevention and as a measure against violence as intended by the Guarantor Authority for Childhood and Adolescence (physical violence, psychological violence, gender-based violence, sexual violence, assisted violence, pathology care violence – including neglect, and hypercare –) and should be adapted to a multi-ethnic and multicultural environment taking into account gender variation, concerning for example, genital female cutting.
To reinforce territorial networks between public (Roma Capitale social services and health services of Regione Lazio) and private facilities working to curb violence against minors in the metropolitan area of Rome. This includes creating a third layer of service in support of preventive services and of emergence and care of foreign minors (including MISNA), of victims or potential victims of violence and of their families.
To reduce organisational and cultural barriers to access to social services in Roma Capitale and to healthcare services in Regione Lazio for the prevention and contrast of violence against minors.
- GOVERNMENT AGENCY: REGIONE LAZIO
BANDO : Protocollo di Intesa Regione Lazio e gli Istituti Fisioterapici Ospitalieri sottoscritto in data 10 maggio 2016 (n. 18902 del 18/05/2016 Reg.Cron.)
TITLE: Operational research project for promoting scientific cooperation in Tigray – Ethiopia
GROUP
IFO – San Gallicano IRCCS
P.I Prof. Aldo Morrone
ABSTRACT
The general objective of this operational research is to establish new scientific collaborations with health and biomedic research facilities in Tigray, Ethiopia; to promote the enhancement of translational clinical research, technological shift, and dissemination of new scientific knowledge through clinical research; to support specialist and clinical-scientific training of local workforce; to support local health authorities efforts in achieving health and healthcare related Sustainable Development Goals (SDGs) agreed by the United Nations.
- ENTE: LAZIO INNOVA
BANDO : Avviso Pubblico “Gruppi di ricerca 2020” - POR FESR Lazio 2014-2020 - Azione 1.2.1 - approvato con
Determinazione n. G08487 del 19/07/2020
TITLE: Evaluation of the efficacy of a product based on Ozonated Oil, Hyaluronic Acid, and Antioxidants in the healing process of fragile patients using Advanced Non-Invasive Diagnostic techniques
GROUP
San Gallicano IRCCS
P.I. Dott. Pasquale Frascione
Partner Fondazione Policlinico Universitario Agostino Gemelli IRCCS
ABSTRACT
The project aims to experimentally evaluate the biological effects of a solution containing ozone, hyaluronic acid, and a pool of antioxidants on the epidermis, dermis, and cutaneous capillary system during the healing process in elderly patients (over 70) suffering from epithelial skin cancer (Squamous Cell Carcinoma and Basal Cell Carcinoma). The skin of elderly patients with skin cancer is characterized by marked actinic damage with epidermal atrophy, increased dermal elastosis and reduced re-epithelialization capacity with consequent delays in the healing process. The assessment of the healing process will be conducted during the removal of the skin tumour, using non-invasive diagnostic techniques on a sample of about 200 patients over the age of 70.
- AGENCY: LAZIO INNOVA
BANDO : Avviso Pubblico “Gruppi di ricerca 2020” - POR FESR Lazio 2014-2020 - Azione 1.2.1 approvato con Determinazione n. G08487 del 19/07/2020
TITLE: Pathway for assigning support to fragile people
GROUP
IFO - San Gallicano IRCCS
P.I. Prof. Aldo Morrone
Partner: Roma Tre University
ABSTRACT
SPES is within the Life Sciences AdS. The general objective is to build a health protocol for the reception of vulnerable people, with the support of an easy-to-access software app, to be tested during Covid-19. The app aims to collect, manage, and analyse protocol-related data, making them accessible to healthcare facilities and to vulnerable people in a safe, effective, and efficient way, without compromising privacy. The project integrates several IT services for the general population and data analysis to constantly improve the service. ISG coordinates the project, is responsible for the infectious disease screening and for testing the level of accessibility to the software’s and to the training/health information activity. EC jointly with ISG will define the system’s requirements and provide support for its use. RM3 will design and develop a prototype of the app, following ISG’s guidelines.
- AGENCY: MISE - Directorate General for the Protection of Industrial Property Italian Patent and Trademark Office Ministry of Economic Development DIV. I General Affairs and Communication
TITLE. Technology Transfer Office IFO – TTO IFO
GROUP: IFO Regina Elena National Cancer Institute IRCCS and San Gallicano IRCCS IRE-ISG
P.I. Prof. Gennaro Ciliberto
ABSTRACT
Strengthening of UTTs to allow greater focus on transfer and protection of industrial properties pertaining to certain productive sectors and to support activities for the enhancement of industrial property titles. The aim is to increase the opportunities for contact and promotion towards the industrial sector, as well as to increase activities and initiatives aimed at favouring the technological transfer of the aforementioned titles.
- GOVERNEMENT AGENCY: Ministry of Health of Italy
TITLE: Can biological agents withdrawn in psoriatic arthritis (PsA) patients after a stable remission of arthritis is achieved? A clinical, radiological and ultrasonographic study.
GROUP: IFO - San Gallicano Institute IRCCS P.I. Dr. Dario Graceffa
ABSTRACT
The prevalence of PsA in patients with psoriasis has been estimated to be up to 30%. PsA can erode and destroy affected joints leading to loss of functional abilities and a considerable decline in quality of life. Moreover, psoriasis is often associated with various comorbities; the most frequently reported are cardiovascular and dismetabolic disorders. TNF blockers provide to achieve absent or very low disease activity, also slowing the progression of related comorbidities. However, these therapies are associated with a marked increase in the direct costs of the treatment and patients are exposed to potentially life threatening adverse events. Unfortunately, few studies have been conducted addressing treatment algorithms in PsA. Furthermore, no standardized criteria for clinical remission in PsA patients are available. Cantini et al. (2008) have defined remission criteria for PsA, adapting the American College of Rheumatology (ACR) criteria for rheumatoid arthritis and showed that remission may be sustained in PsA despite treatment interruption. The use of ultrasound assessment in the early detection of disease recurrence could become necessary to prevent the relapse and direct the clinician’s choice concerning a re-treatment regimen. Potential benefits of this approach would include prevention of drug side effects, removal of risks associated with prolonged immunosuppression and significant financial savings.
- GOVERNMENT AGENCY: Ministry of Health of Italy
TITLE: A radiogenomic approach to assess treatment response to anti-PD-1 immune checkpoint inhibitor in metastatic melanoma patients using CT texture analysis combined with tumor molecular profile as potential predictive biomarker: a pilot study
GROUP: IFO - San Gallicano Institute IRCCS P.I. Dr. Antonino Guerrisi
ABSTRACT
Immunotherapy is currently changing the landscape of oncology and it is improving overall and progressive free survival for metastatic melanoma. CT imaging is generally used to assess treatment response according to RECIST 1.1. However, due to the atypical patterns of response generated by immunotherapy, a pseudo-progression can occur highlighting the limits of these criteria. There is no unanimous consensus to which biomarker should be used to drive clinical decisions in melanoma patients and more concerns remain about intra-tumour heterogeneity. CT texture Analysis (CTTA) permits to extract quantitative imaging features providing quantitative data on tumour phenotype and microenvironment. The goal of this study is to investigate if CTTA combined with tumour molecular profile could be use as potential predictor of treatment response in metastatic melanoma patients. A radio genomic approach will be explored to improve evidence-based clinical decision support.